A Divergent Approach to the Synthesis of 3-Substituted-2-pyrazolines: Suzuki Cross-Coupling of 3-Sulfonyloxy-2-pyrazolines
β Scribed by Grimm, Jonathan B.; Wilson, Kevin J.; Witter, David J.
- Book ID
- 121858783
- Publisher
- American Chemical Society
- Year
- 2009
- Tongue
- English
- Weight
- 963 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0022-3263
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The reaction of dibenzylideneacetones or E,E-cinnamylidene-acetophenones and hydrazine hydrate provided 1-propionyl derivatives of 5-aryl-3-styryl-2-pyrazolines and 3-aryl-5-styryl-2-pyrazolines. These unsaturated ketones afforded 1-(2-carboxyphenyl) or 1-(4-carboxyphenyl) 5-aryl-3-styryl-2-pyrazoli