A direct synthesis of 5-fluorocytosine and its nucleosides using trifluoromethyl hypofluorite
✍ Scribed by Robins, Morris J.; Naik, S. R.
- Book ID
- 118258801
- Publisher
- The Royal Society of Chemistry
- Year
- 1972
- Tongue
- English
- Weight
- 128 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0022-4936
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## Abstract A new route is presented to prepare analogs of nucleosides homologated at the 3′‐ and 5′‐positions. This route, applicable to both the D‐ and L‐enantiomeric forms, is suitable for the preparation of monomeric bis‐homonucleosides needed for the synthesis of oligonucleotide analogs. It be
Synthesis of lipid A 1 isolated from Helicobacter pylori strain 206-1 has been achieved in 2.2% total yield through 14 steps from d-glucosamine by employing a p-(tri¯uoromethyl)benzyl group for protection of the hydroxy group on the 3-hydroxy fatty acid residue. The synthetic specimen was identical