𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A direct confirmation of the specificity of mutation frequency decline for suppressor mutations

✍ Scribed by Clarke, Colin H.

Book ID
104693872
Publisher
Springer
Year
1978
Tongue
English
Weight
196 KB
Volume
162
Category
Article
ISSN
0026-8925

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✦ Synopsis

In a phage T7-resistand and galactose-sensitive derivative of E. coli B/r trp- it has been possible to show that MFD for UV-induced mutations is specific for Trp+ reversions (mainly of an ochre suppressor-containing type) but is without effect on galactose-resistant or D-fucose-resistant (ara Cc) forward mutations.

πŸ“œ SIMILAR VOLUMES

Ultraviolet photoproducts at the ochre s
Ultraviolet photoproducts at the ochre suppressor mutation site in the gln U gene of Escherichia coli: Relevance to β€œmutation frequency decline”
✍ Garvey, Nancy ;Witkin, Evelyn M. ;Brash, Douglas E. πŸ“‚ Article πŸ“… 1989 πŸ› Springer 🌐 English βš– 939 KB

Ochre suppressor mutations induced by UV in the Escherichia coli glnU tRNA gene are CG to TA transitions at the first letter of the anticodon-encoding triplet, CAA. Premutational UV photoproducts at this site have long been known to exhibit an excision repair anomaly ("mutation frequency decline" or