Mutation frequency decline in a rel strain of E. coli B/r
β Scribed by Engstrom, Joyce E. ;Bockrath, Richard C.
- Publisher
- Springer
- Year
- 1980
- Tongue
- English
- Weight
- 450 KB
- Volume
- 178
- Category
- Article
- ISSN
- 0026-8925
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Mutation frequency decline (MFD) in Escherichia coli was examined to demonstrate repair of targeting photoproducts during the post-UV incubation required in this process. Repair of mutation-targeting cyclobutane pyrimidine dimers (T <> C) was demonstrated when a correlation was established between t
In Escherichia coli B/r the expression of UV inducible (SOS) functions is under the control of the recA and lexA genes. In this study we have characterized mutants which are altered in their ability to express SOS functions. These mutants were isolated as UV resistant UV nonmutable (Rnm) derivatives
Ochre suppressor mutations induced by UV in the Escherichia coli glnU tRNA gene are CG to TA transitions at the first letter of the anticodon-encoding triplet, CAA. Premutational UV photoproducts at this site have long been known to exhibit an excision repair anomaly ("mutation frequency decline" or