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A Direct and General Synthesis of 5-Substituted 3-Trifluoromethyl-1,2,4-triazoles via the Three-component Condensation Reaction of Ethyl Trifluoroacetate, Hydrazine and Amidines

โœ Scribed by Funabiki, Kazumasa; Noma, Naoko; Kuzuya, Gouhaku; Matsui, Masaki; Shibata, Katsuyoshi


Book ID
121206760
Publisher
Science Reviews 2000 Ltd
Year
1999
Tongue
English
Weight
97 KB
Volume
5
Category
Article
ISSN
0308-2342

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A Direct and General Synthesis of 5-Substituted 3-Trifluoromethyl-1,2,4-triazoles via the Three Component Condensation Reaction of Ethyl Trifluoroacetate, Hydrazine and Amidines. -Because of their potent biological and physiological activities a general and practicable one-pot reaction to 5-substit