✦ LIBER ✦

ChemInform Abstract: A Direct and General Synthesis of 5-Substituted 3-Trifluoromethyl-1,2,4-triazoles via the Three Component Condensation Reaction of Ethyl Trifluoroacetate, Hydrazine and Amidines.

✍ Scribed by Kazumasa Funabiki; Naoko Noma; Gouhaku Kuzuya; Masaki Matsui; Katsuyoshi Shibata

Publisher: John Wiley and Sons
Year: 2010
Weight: 29 KB
Volume: 30
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199938140

No coin nor oath required. For personal study only.

✦ Synopsis

A Direct and General Synthesis of 5-Substituted 3-Trifluoromethyl-1,2,4-triazoles via the Three Component Condensation Reaction of Ethyl Trifluoroacetate, Hydrazine and Amidines.

-Because of their potent biological and physiological activities a general and practicable one-pot reaction to 5-substituted trifluoromethyltriazoles (III) is developed. -

📜 SIMILAR VOLUMES

ChemInform Abstract: Rapid Synthesis of

ChemInform Abstract: Rapid Synthesis of 1,3,5-Substituted 1,2,4-Triazoles from Carboxylic Acids, Amidines, and Hydrazines.

✍ Georgette M. Castanedo; Pamela S. Seng; Nicole Blaquiere; Sean Trapp; Steven T. 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 85 KB

ChemInform Abstract: Synthesis of Fully

ChemInform Abstract: Synthesis of Fully Substituted Iminolactones (IV) via a Three-Component Condensation of Isocyanides and Acetylenic Esters with 2-Bromo-1-(4-bromophenyl)ethanone.

✍ Ahmad Shaabani; Ebrohim Soleimani; Afshin Sarvary 📂 Article 📅 2008 🏛 John Wiley and Sons ⚖ 21 KB 👁 1 views

ChemInform Abstract: Synthesis of Annula

ChemInform Abstract: Synthesis of Annulated 2H-Indazoles and 1,2,3- and 1,2,4-Triazoles via a One-Pot Palladium-Catalyzed Alkylation/Direct Arylation Reaction.

✍ Benoit Laleu; Mark Lautens 📂 Article 📅 2009 🏛 John Wiley and Sons ⚖ 34 KB

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

ChemInform Abstract: An Unprecedented an

ChemInform Abstract: An Unprecedented and Concise Method for the Synthesis of 1,3-Thiazino-[3,4-a][1,3]benzimidazoles via a Three-Component Reaction.

✍ Abdolali Alizadeh; Zohreh Noaparast; Hamideh Sabahnoo; Nasrin Zohreh 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 18 KB 👁 1 views

## Abstract The novel and simple protocol allows the synthesis of the biologically interesting title compounds (IV).

ChemInform Abstract: Zirconium-Catalyzed

ChemInform Abstract: Zirconium-Catalyzed Nagata Reaction for the Synthesis of 2-Aryl-1,3,2-aryldioxaborins via a Mild Three-Component Condensation of Phenols, Aldehydes, and Boronic Acid.

✍ Hongchao Zheng; Dennis G. Hall 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 28 KB 👁 1 views

## Abstract A mild approach is developed with an electron‐deficient boronic acid (I) as coupling component.

ChemInform Abstract: Metal- and Base-Fre

ChemInform Abstract: Metal- and Base-Free Three-Component Reaction of Ynones, Sodium Azide and Alkyl Halides: Highly Regioselective Synthesis of 2,4,5-Trisubstituted 1,2,3-NH-Triazoles.

✍ Jihui Li; Yuanqing Zhang; Dong Wang; Wen Wang; Tingting Gao; Lu Wang; Jiting Li; 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 36 KB 👁 1 views