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A diastereoselective phenylselenium-induced lactamization of olefinic amides. A possible route to α-and β-amino acid derivatives

✍ Scribed by Sung-Kee Chung; Tae-Heum Jeong; Dong-Ho Kang

Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
287 KB
Volume
8
Category
Article
ISSN
0957-4166

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✦ Synopsis

The organoselenium-induced cyclofunctionalization of (S)-N-(0t,13-unsaturatedacyl)prolinamides was found to produce with a high degree of chirality transfer, 7-and 6-membered bislactam derivatives depending on the substitution pattern of the starting material.

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