✍ Scribed by M. SHIMANO; A. I. MEYERS
No coin nor oath required. For personal study only.
Diastereoselective 1,6-Additions of Lithium Amides to Naphthyloxazolines. A Route to Novel δ-Amino Acid Derivatives.
-The title reaction is performed with oxazolines such as (I), which may be useful for the synthesis of novel aminocarboxylic acids such as (IX) . In the case of methyl iodide or triflate as electrophile a higher amount of the other diastereomer (XI) is observed. It is noteworthy that DMPU instead of HMPA as cosolvent mainly gives starting material and no meaningful levels of the desired 1,6-adduct. The structure of compounds such as (V) is determined by X-ray analysis.
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v