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A Diastereoselective, Nucleophile-Promoted Aldol-Lactonization of Ketoacids Leading to Bicyclic-β-Lactones

✍ Scribed by Liu, Gang; Shirley, Morgan E.; Romo, Daniel


Book ID
111981482
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
748 KB
Volume
77
Category
Article
ISSN
0022-3263

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ChemInform Abstract: Double Diastereosel
✍ Kay A. Morris; Kevin M. Arendt; Seong Ho Oh; Daniel Romo 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 63 KB 👁 1 views

## Abstract It is demonstrated, that aldol lactonization of ω‐carbonyl substituted carboxylic acids with Mukaiyama′s reagent can proceed with double diastereodifferentiation.