A degradation product of halobetasol propionate—Characterization and structure
✍ Scribed by Giancarlo Cravotto; Giovanni B. Giovenzana; Norberto Masciocchi; Giovanni Palmisano; Paolo Volante
- Book ID
- 116892071
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 383 KB
- Volume
- 72
- Category
- Article
- ISSN
- 0039-128X
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We report the identification and characterization of a novel degradation product associated with PEGylation of a recombinant protein. After several months of storage at 2 • C-8 • C, an unexpected increase was observed in the proportion of an impurity that eluted with the native unPEGylated protein b