A cytological study of the anterior hypophysis of the dog with particular reference to the presence of a fourth cell type

✍ Scribed by Hartmann, J. Francis ;Fain, W. R. ;Wolfe, J. M.

• Publisher: John Wiley and Sons
• Year: 1946
• Tongue: English
• Weight: 922 KB
• Volume: 95
• Category: Article
• ISSN: 0003-276X
• DOI: 10.1002/ar.1090950104

✦ Synopsis

The reported existence of a fourth cell type that is present in the anterior hypophysis of many animals in addition to the traditional acidophiles, basophiles and chromophobes is one of the more interesting aspects of hypophyseal cytology. I n a study of cyclic histological variations in the anterior hypophysis of the female dog (Wolfe, Cleveland and ('amp- hell, '33), such a fourth cell type was described. Cells of this type contained granules that stained selectively with erythrosin in the erythrosin-orange G-aniline blue method of Cleveland and Wolfe ( '32). The erythrosin-stained cells were referred to as Type 11, and were considered to be of a basophilic character.

Subsequently, Dawson and Friedgood ( '38) discovered ill the anterior hypophyses of female rabbits and cats an additional cell type with a special affinity for azocarmine. Their findings were followed by investigations revealing the presence of similar cells in the anterior lobes of several other species. They have been reported in the hypophpses of the opossum, ferret and monkey by Dawson ('38 a i d '42), in the armadillo by Oldham ( '38), in various orders of birds by