Heteromorphisms of chromosomes 3, 4, 13-15, 21-22, and Y were studied in a population of 374 mentally retarded patients from diverse ethnic groups. A significant variation in the size of the Y chromosome was found among different racial groups, those of the Orientals and Filipinos being larger than
A cytogenetic survey of an institution for the mentally retarded
β Scribed by Janice Matsuura; Martha Mayer; Patricia Jacobs
- Publisher
- Springer
- Year
- 1978
- Tongue
- English
- Weight
- 506 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0340-6717
No coin nor oath required. For personal study only.
β¦ Synopsis
Heteromorphisms of chromosomes 1, 9, and 16 were studied by C-banding in a population of 403 mentally retarded individuals from diverse ethnic groups. A significant difference in the distribution of heteromorphisms was found among the different racial groups. The Orientals had a larger C-band on chromosome 1 and a smaller C-band on chromosome 9 than the other racial groups while the Caucasians had a larger C-band on chromosome 9. The Oriental group also had a significantly greater proportion of inverted C-bands. No differences were found in the distribution of C-band heteromorphisms among different etiologic categories of mental retardation.
π SIMILAR VOLUMES
A cytogenetic survey of all 588 patients in Strathmont Training Centre, an Australian hospital for the mentally retarded, was carried out. Abnormal karyotypes were found in 90 (15.3%) patients, of whom 73 (12.4%) had clinical Down syndrome, 12 (2.04%) other autosomal abnormalities, and 5 (0.85%) sex
## Abstract From December 1977 until April 1978 a hepatitis A outbreak occurred in an institution for the mentally retarded. The institution housed 311 residents and had a staff of 308. The outbreak was studied by enzymeβlinked immunosorbent assays for hepatitis A antigen and antibodies, and by liv
A cytogenetic survey was carried out on 200 patients with mental retardation and multiple congenital anomalies, and on 200 normal adult controls. Patients with a known syndrome were excluded from the survey. Chromosome analyses were carried out on 'blind-coded' slides using the ASG banding technique