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A cytogenetic survey of 14,835 consecutive liveborns

✍ Scribed by Tohru Maeda; Michiko Ohno; Akira Matsunobu; Kyoko Yoshihara; Noriko Yabe

Publisher
Nature Publishing Group
Year
1991
Tongue
English
Weight
766 KB
Volume
36
Category
Article
ISSN
1435-232X

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A cytogenetic survey of all 588 patients in Strathmont Training Centre, an Australian hospital for the mentally retarded, was carried out. Abnormal karyotypes were found in 90 (15.3%) patients, of whom 73 (12.4%) had clinical Down syndrome, 12 (2.04%) other autosomal abnormalities, and 5 (0.85%) sex

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Heteromorphisms of chromosomes 3, 4, 13-15, 21-22, and Y were studied in a population of 374 mentally retarded patients from diverse ethnic groups. A significant variation in the size of the Y chromosome was found among different racial groups, those of the Orientals and Filipinos being larger than

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Heteromorphisms of chromosomes 1, 9, and 16 were studied by C-banding in a population of 403 mentally retarded individuals from diverse ethnic groups. A significant difference in the distribution of heteromorphisms was found among the different racial groups. The Orientals had a larger C-band on chr