Design and synthesis of a novel bis-crow
โ
H. Dugas; P. Brunet; J. Desroches
๐
Article
๐
1986
๐
Elsevier Science
๐
French
โ 209 KB
A new bis-crown ether carrier molecule 3b with an ammonium tail was synthesized to mimic some of the properties of (Na+,K+)-ATPase activity. At low pH, the ammonium salt shows stabilization by intramolecular hydrogen bonding with the 18-crown-6 portion of the molecule and the compound has some selec