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A critical role for interleukin-6 family-mediated Stat3 activation in osteoblast differentiation and bone formation

โœ Scribed by Shousaku Itoh; Nobuyuki Udagawa; Naoyuki Takahashi; Fumio Yoshitake; Hiroko Narita; Shigeyuki Ebisu; Katsuhiko Ishihara

Book ID
116319680
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
629 KB
Volume
39
Category
Article
ISSN
8756-3282

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## Abstract The neuropeptide Y (NPY) system has been implicated in the regulation of bone homeostasis and osteoblast activity, but the mechanism behind this is unclear. Here we show that Y1 receptor signaling is directly involved in the differentiation of mesenchymal progenitor cells isolated from