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A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin

โœ Scribed by DavidA Gewirtz

Book ID
118509306
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
262 KB
Volume
57
Category
Article
ISSN
0006-2952

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โœ Rabindranath Ray; Bimal K. Chakraborty; Kaushik Ray; Sheela Mukherji; Jayasree R ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Springer ๐ŸŒ English โš– 720 KB

In the present study, anthracycline antitumor antibiotics (e.g. adriamycin and nogalamycin), the potent RNA synthesis inhibitors and cycloheximide, the protein synthesis inhibitor, have been used to understand the events of biosynthesis and processing of major UsnRNAs (U1-U6). The anthracyclines inh