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A cost-benefit analysis of preimplantation genetic diagnosis for carrier couples of cystic fibrosis

โœ Scribed by L.B. Davis; S.J. Champion; S.O. Fair; L.M. Aquino; P.M. Blanchfield; A.M. Garber


Book ID
116472156
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
66 KB
Volume
88
Category
Article
ISSN
1556-5653

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Clinical application of preimplantation
โœ V. Goossens; K. Sermon; W. Lissens; M. Vandervorst; A. Vanderfaeillie; M. De Rij ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 114 KB ๐Ÿ‘ 2 views

Cystic fibrosis (CF) is an autosomal recessive disease characterized by obstruction and chronic infections of the respiratory tract and pancreatic insufficiency. The gene was cloned in 1989 and the most frequent mutation was shown to be the delta F508 mutation. During PGD, embryos obtained in vitro