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A Correlation Between the Reduced Expression of E-Cadherin and Promoter Hypermethylation in Oral Squamous Cell Carcinoma

✍ Scribed by Sung W. Pyo


Book ID
113737463
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
37 KB
Volume
65
Category
Article
ISSN
1531-5053

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## Abstract Aberrant promoter hypermethylation of tumor‐associated genes leading to their inactivation is a common event in many cancer types. Using a sensitive restriction‐multiplex PCR method, we studied the promoter hypermethylation profile of the __p16, p15, hMLH1, MGMT__ and __E‐cad__ genes in