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A ConvenientMannich-Type One-Pot Synthesis of Pyrimido[6,1-b][1,3,5]thiadiazines

✍ Scribed by Victor V. Dotsenko; Konstantin A. Frolov; Sergey G. Krivokolysko; Alexander N. Chernega; Victor P. Litvinov

Book ID: 106213730
Publisher: Springer Vienna
Year: 2006
Tongue: English
Weight: 279 KB
Volume: 137
Category: Article
ISSN: 0026-9247
DOI: 10.1007/s00706-006-0512-2

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## Abstract An efficient and convenience method has been developed __via__ a one‐pot double Mannich type reaction for the synthesis of the important chiral s‐triazole derivatives: (__S__)‐3‐α‐phenylethyl‐2,4‐dihydro‐5‐aryl‐oxymethyl‐1,2,4‐triazolo [3,4‐__b__] ‐1,3,5 ‐thiadiazines.