✦ LIBER ✦

A convenient synthesis of S-HPMPA

✍ Scribed by Robert R. Webb II; John C. Martin

Publisher: Elsevier Science
Year: 1987
Tongue: French
Weight: 112 KB
Volume: 28
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)96670-x

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✦ Synopsis

_S-HPMPA, (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine 1, a broad spectrum adenine nucleotide antiviral, has been synthesized in 4 steps from S-DHPA 2 (36% overall yield from adenine). S-HPMPA, (_S_)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine

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