A Convenient Synthesis of Protoanemonin.
✍ Scribed by Caroline Crey; Pascal Dumy; Jean Lhomme; Mitsuharu Kotera
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 97 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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📜 SIMILAR VOLUMES
## Abstract A convenient synthesis of the antidepressant paroxetine starting from 1‐benzyl‐4‐piperidone (**2**) is reported. A stereoselective reduction resulted in __cis__‐piperidine‐3‐methanol [(**+**)‐**6**]. The reaction between __cis__‐piperidine‐3‐methanol mesylate (**7**) and sesamol led to
Silver-t-butyl-(N-t-butyloxycarbonyl-2-aminoethyl) phosphate was synthesized. Coupling of this compound with l-palmitoyl-2-oleoyl-glycerol-3-iodohydrin, followed by removal of both protecting groups, gave, after recrystallization (without chromatography) pure I-palmitoyl-2-oleoyl-3-phosphatidylethan