A convenient synthesis of [3-3H]squalene
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Maurizio Ceruti; Giorgio Grosa; Flavio Rocco; Franco Dosio; Luigi Cattel
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Article
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1994
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John Wiley and Sons
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French
β 421 KB
## Abstract [3β^3^H]Squalene and [3β^3^H]β2,3βoxidosqualene, key compounds for studying the biosynthesis of sterols, were synthesized. The main step was a modified Wittig reaction of [1β^3^H]trisnorsqualene aldehyde with a phosphorus ylide to give [3β^3^H]squalene or with a sulfur ylide to give [3β