A convenient strategy for the synthesis of β,γ-unsaturated aldehydes and acids. A construction of skipped dienes

✍ Scribed by Goutam Saha; Manas K. Basu; Seongjin Kim; Young-Ju Jung; Yurdanur Adiyaman; Mustafa Adiyaman; William S. Powell; Garret A. FitzGerald; Joshua Rokach

• Publisher: Elsevier Science
• Year: 1999
• Tongue: French
• Weight: 238 KB
• Volume: 40
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(99)01498-7

✦ Synopsis

A novel strategy is described for the synthesis of l~,¥-unsaturated aldehydes which are the useful synthons for the synthesis of arachidonic acid and other eicosanoid products. These 13,y-unsaturated aldehydes have been used in the total synthesis of arachidonic acid.