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A Convenient Procedure for the Preparation of Amino Acid Hydroxamates from Esters

โœ Scribed by Pirrung, Michael C.; Chau, Joseph H.-L.


Book ID
111921736
Publisher
American Chemical Society
Year
1995
Tongue
English
Weight
269 KB
Volume
60
Category
Article
ISSN
0022-3263

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A one-step conversion of carboxylic acid to hydroxamic acid, under neutral pH conditions is described. This simple, selective and ecient method was applied to a wide range of aliphatic/aromatic carboxylic acid derivatives that contain hydroxyl, halo, ester and other base sensitive groups as substitu