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A convenient preparation of (S)-(−)-4-hydroxy-2-methylcyclopent-2-en-1-one and its application as a chiral synthetic equivalent of 2-methylcyclopent-2-en-1-one in the terpenoid synthesis

✍ Scribed by Michalak, Karol; Wicha, Jerzy


Book ID
124139461
Publisher
Elsevier Science
Year
2014
Tongue
French
Weight
628 KB
Volume
70
Category
Article
ISSN
0040-4020

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A novel strategy for the enantioselective synthesis of several a-hydroxy carboxylic acids by the nucleophilic alkylation of chiral 3-hydroxy-(YS, 8aS)-perhydropyrrolo [2,1-C] [1,4] oxazin -4 one is reported.