𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A convenient preparation of glycolic-1-14C acid

✍ Scribed by Lane A. Clizbe; Elmer J. Reist

Publisher
John Wiley and Sons
Year
1992
Tongue
French
Weight
213 KB
Volume
31
Category
Article
ISSN
0022-2135

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

An operationally simple preparation of glycolic‐1‐^14^C acid from ^14^CO~2~ has been developed using a tin‐lithium exchange reaction to generate the required hydroxymethyl anion equivalent. Glycolic‐1‐^14^C acid was then produced in high yield and good radiochemical purity upon hydrogenolytic removal of the benzyl group.

📜 SIMILAR VOLUMES

A convenient preparation of pentachloron
A convenient preparation of pentachloronitrobenzene-U-14C
✍ H. H. Kaegi 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 French ⚖ 106 KB

## Abstract Starting with benzene‐U‐^14^C pentachloronitrobenzene‐U‐^14^C has been prepared by nitration followed by chlorination with antimony pentachloride in the presence of aluminum chloride.

Preparation of 1-Hydroxycyclopentanecarb
Preparation of 1-Hydroxycyclopentanecarboxylic Acid Derivatives from a Chiral Equivalent of Glycolic Acid
✍ Sokol Abazi; Liliana Parra Rapado; Kurt Schenk; Philippe Renaud 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 197 KB 👁 2 views

The stereoselective preparation of 1-hydroxycyclopenta-precursors are easily synthesized by two consecutive enolate alkylations. Excellent stereochemical control for the necarboxylic acid derivatives is reported. The key reaction is either a radical cyclization or a radical annulation mediated quate

Reaction of 14CO2 with grignard reagents
Reaction of 14CO2 with grignard reagents to form either carboxylic acids or ketones. A novel convenient route to [2-14C] glycerol and [1-14C] Glycolic acid
✍ B. Wirz; W. Küng 📂 Article 📅 1983 🏛 John Wiley and Sons 🌐 French ⚖ 493 KB

The reaction of C02 with GRIGNARD reagents carrying an ether grouping in a sterically suitable position can be directed to afford predominantly either the carboxylic acid or the symmetrical ketone. Thus, the magnesiumorqanic compounds prepared from chloromethyl-methyl ether, benzyl-chloromethyl ethe

Synthesis of homovanillic acid-2−14C, ho
Synthesis of homovanillic acid-2−14C, homoprotocatechuic acid-2−14C, 3′, 4′-dihydroxymandelic acid-2−14C and 1-(4 hydroxy-3-methoxyphenyl)-ethylene glycol-1−14C
✍ A. A. Liebman; D. H. Malarek; A. M. Dorsky; H. H. Kaegi 📂 Article 📅 1971 🏛 John Wiley and Sons 🌐 French ⚖ 493 KB 👁 1 views

Specifically labelled phenylacetic acid and mandelic acid derivatives, metabolites of L-Dopa, have been synthesized via the intermediary labelled benzyl alcohols, which were prepared by reduction of the methyl esters of the appropriate benzoic acids. The benzyl alcohols have been converted to the co

Preparation of carbon-14 labelled amprop
Preparation of carbon-14 labelled ampropylfos (1-[14C]-α-aminopropanephosphonic acid)
✍ Harry R. Hudson; Fatima Ismail 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 71 KB 👁 1 views

## Abstract 1‐[^14^C]‐__α__‐Aminopropanephosphonic acid, with a specific activity of 1.736 µCi mg^−1^, has been prepared from 1‐[^14^C]‐propanal, triphenyl phosphite, and benzyl carbamate by interaction in toluene in the presence of boron trifluoride‐etherate, followed by hydrolysis. The product wa