A Convenient Preparation of Arylmaleic Anhydrides
β Scribed by Hill, Richard K.
- Book ID
- 120347780
- Publisher
- American Chemical Society
- Year
- 1961
- Tongue
- English
- Weight
- 424 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
a b s t r a c t Palladium-catalyzed arylation of fumaric acid with aryl iodides is found to be a very simple, economic and scalable approach to arylmaleic anhydrides. The reaction is facilitated by the presence of donor moieties on the aryl fragment and does not occur with strong acceptor groups.
## Bridged N-protected p-amino acids have been regioselectively prepared from the corresponding bicyclic monoesrers. The subsequent cyclisation by thionyl chloride produced rhe &sired bridged azatricyclic anhydrides which are versatile substrates for the synthesis of dipeptides; they are also conver