A convenient one-step method for the deprotection and esterification of triphenylmethyl ethers
✍ Scribed by Stephen C Bergmeier; Kristján M Arason
- Book ID
- 104210604
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- French
- Weight
- 213 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
We have discovered a simple one-pot procedure to convert trityl ethers into esters, using the corresponding acid chloride as the only reagent.
📜 SIMILAR VOLUMES
A Simple and Convenient Method for the Deprotection of Tetrahydropyranyl Ether Using Iodine in Methanol. -Iodine in methanol selectively cleaves primary and secondary tetrahydropyranyl and 4,4'-dimethoxytrityl protecting groups. Other protecting groups (such as benzoyl, benzyl, tert-butyloxycarbony
Seoul 131, Korea Reaction of carboxylic acids with equimolar amounts of alkyl chloroformate and triethylamine in the presence of a catalytic amount of 4-dimethylaminopyridine affords the corresponding esters in high yields without the formation of the symmetrical anhydride in most carboxylic acids.