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A convenient method for14C-labeling ofN-(2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-1H-pyrrole-2-carboxamide-[carboxy-14C] as CCK-A antagonist

✍ Scribed by Nader Saemian; Gholamhossein Shirvani

Book ID
113073172
Publisher
Springer
Year
2011
Tongue
English
Weight
243 KB
Volume
292
Category
Article
ISSN
1588-2780

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📜 SIMILAR VOLUMES

Synthesis of carbon-14 analogue of N-(1-
Synthesis of carbon-14 analogue of N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-benzamide-[carboxyl-14C] as CCK-A antagonist
✍ Nader Saemian; Gholamhossein Shirvani; Hojatollah Matloubi 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 96 KB 👁 1 views

## Abstract __N__‐(1‐methyl‐2‐oxo‐5‐phenyl‐2,3‐dihydro‐1H‐benzo[e][1,4]diazepin‐3‐yl)‐benzamide‐[carboxyl‐^14^C] has been synthesized from benzonitrile‐[cyano‐^14^C]. Copyright © 2005 John Wiley & Sons, Ltd.

Synthesis of N-(2,3-dihydro-1-[14C]methy
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✍ Hojatollah Matloubi; Ali Khalaj; Reza Dowlatabadi; Gholamhossein Shirvani 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 74 KB 👁 1 views

## Abstract Two benzodiazepine CCK antagonists __N__‐(2,3‐dihydro‐1‐[^14^C]methyl‐2‐oxo‐5‐phenyl‐1H 1,4‐benzodiazepin‐3‐yl)‐benzamide **2** and __N__‐(2,3‐dihydro‐1‐[^14^C]methyl‐2‐oxo‐5‐phenyl‐1H‐1,4‐benzodiazepin‐3‐yl)‐[^14^C]methyl‐benzamide **3** were synthesized in high yields through the reac

Synthesis of 14C-labeled 3-{[1-ethoxycar
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The title compound, CGS 148248, was synthesized with a '%-label in the azepine ring in 14 steps starting with l-bromo-3-phenylpropane (1> and K1%N in an overall yield of 1.31%. The reaction of I with K 1 k N yielded the nitrile 2 which upon hydrolysis followed by ring closure gave a-tetral~ne-l-~~c

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## Abstract A group of radioactive 1,4‐benzodiazepine derivatives have been synthesized from glycine‐1‐^14^C. The subject compounds are labeled with carbon‐14 in the 2‐position of the 1,4‐benzodiazepine ring system.

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## Abstract ^14^C‐Labelled (S)‐(+)‐6‐(2‐chlorophenyl)‐3‐cyclopropanecarbonyl‐8,11‐dimethyl‐2,3,4,5‐ tetrahydro‐8H‐pyrido[4′,3′:4,5]thieno[3,2‐f][1,2,4]triazolo[4,3‐a][1,4] diazepine (^14^C‐E6123), a platelet activating factor receptor antagonist for studying the pharmacokinetic profile of E6123, wa