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A convenient method for the synthesis of radioactively labelled aryl glycosides

✍ Scribed by Simon D. J. Griffin; Iain A. Donaldson

Publisher
John Wiley and Sons
Year
1993
Tongue
French
Weight
313 KB
Volume
33
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

Fluoride‐directed methylation of the aryl hydroxyl of hydroxyphenyl glycosides with radioactive methyl iodide allows the incorporation of label under mild conditions that preserve the glycosidic link. The effectiveness of this approach has been demonstrated by the synthesis of two ^14^C‐labelled aryl α‐glycosides.

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