In continuation of our studies [1,21 on the chemical properties of the labile adduct (11, formed from triphenylphosphine and diethylazodicarboxylate, we reacted this quasi-l,3 salt with one equivalent of diethylmalonate in methanol at 0.C. Gas chromatographic follow up of the reaction showed disappe
A convenient method for enzymatic benzyl-alkyl transesterification under mild neutral conditions
โ Scribed by Arie L. Gutman; Eleonora Shkolnik; Michal Shapira
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- French
- Weight
- 428 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0040-4020
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โฆ Synopsis
Abstru:
Lipases from Candida cylindracea and from Pseudomonas fluofescens efficiently catalyse the benzyl to alkyl transesterification in organic solvents under mild conditions in nearly quantitative yields.
๐ SIMILAR VOLUMES
An efficient and chemoselective sulfonamide N-alkylation of sulfonyl ureas is described. The sulfonyl urea derivatives, prepared in situ by the addition of an amine to an arylsulfonyl isocyanate, are selectively alkylated in excellent yields under neutral and mild conditions by treatment with trialk
Reagents which are sufficiently selective to distinguish between functional groups of the same class are exceedingly valuable in syntheses involving multlfunctlonal molecules, since they permit operations