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A convenient configuration for safe and efficient radio-HPLC of 99mTc-radiopharmaceuticals

✍ Scribed by C. Van Nerom; G. Bormans; B. Cleynhens; M. De Roo; A. Verbruggen


Book ID
103911245
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
834 KB
Volume
7
Category
Article
ISSN
0731-7085

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An improved method for the preparation of 99mTc-radiopharmaceuticals containing the TEN multiple bond, in sterile and apyrogen conditions, is described. This method is based on the reaction of [99mTc]pertechnetate with ligands derived from S-methyl dithiocarbazate [H2N--N(R)~C(=S)SCH 3 (R = H, CH3]