A simple and efficient synthesis of 2-(cyclohexylamino)-6,7-dihydro-3-aryl-1H-indole-4(5H)-ones was achieved via a one-pot multi-component reaction of cyclohexyl isocyanide, an aldehyde, a 1,3-dicarbonyl compound, and ammonium acetate in the presence of a catalytic amount of KHSO 4 in acetonitrile.
A convenient and mild synthesis of new 2-aryl-3-hydroxy-6,7-dihydro-1H-indol-4(5H)-ones via a one-pot, three-component reaction in water
✍ Scribed by Khalafy, Jabbar; Etivand, Nasser; Dilmaghani, Shadi; Ezzati, Mahnaz; Marjani, Ahmad Poursattar
- Book ID
- 121850351
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- French
- Weight
- 254 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0040-4039
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