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A novel and facile synthesis of 2-(cyclohexylamino)-6,7-dihydro-3-aryl-1H-indole-4(5H)-ones via a one-pot multi-component reaction

✍ Scribed by Majid M. Heravi; Bita Baghernejad; Hossein A. Oskooie; Rahim. Hekmatshoar

Publisher
Elsevier Science
Year
2008
Tongue
French
Weight
158 KB
Volume
49
Category
Article
ISSN
0040-4039

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✦ Synopsis

A simple and efficient synthesis of 2-(cyclohexylamino)-6,7-dihydro-3-aryl-1H-indole-4(5H)-ones was achieved via a one-pot multi-component reaction of cyclohexyl isocyanide, an aldehyde, a 1,3-dicarbonyl compound, and ammonium acetate in the presence of a catalytic amount of KHSO 4 in acetonitrile.

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