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A continuous fluorimetric method to monitor the enzymatic hydrolysis of medicinal esters

โœ Scribed by Aline Salvi; Joachim M. Mayer; Pierre-Alain Carrupt; Bernard Testa


Book ID
118412799
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
541 KB
Volume
15
Category
Article
ISSN
0731-7085

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## Abstract The first direct enzymatic method is reported for the synthesis of __cis__ and __trans__ ฮฒโ€amino acid enantiomers through the lipaseโ€catalyzed enantioselective hydrolysis of alicyclic ฮฒโ€amino esters in organic media. High enantioselectivities (__E__ usually >100) were observed when the