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A continuous fluorescence assay for the determination of calcium-dependent secretory phospholipase A2 activity in serum

✍ Scribed by Francis H.C. Tsao; Dhanansayan Shanmuganayagam; Derek K. Zachman; Mehdi Khosravi; John D. Folts; Keith C. Meyer

Book ID
116347492
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
637 KB
Volume
379
Category
Article
ISSN
0009-8981

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Phospholipase A 2 (PLA 2 ) is an enzyme that cleaves fatty acids from the sn-2 position of membrane phospholipids. Intracellular PLA 2 has been shown to be important for the generation of arachidonic acid, which leads to the synthesis of a wide range of eicosanoid paracrine hormones. Furthermore, se