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A Consensus Neural Network-Based Technique for Discriminating Soluble and Poorly Soluble Compounds

✍ Scribed by Manallack, D.T.; Tehan, B.G.; Gancia, E.; Hudson, B.D.; Ford, M.G.; Livingstone, D.J.; Whitley, D.C.; Pitt, W.R.


Book ID
125942641
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
132 KB
Volume
43
Category
Article
ISSN
0095-2338

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✍ Karlβ€…J. Box; Gergely VΓΆlgyi; Rebeca Ruiz; Johnβ€…E. Comer; Krisztina TakΓ‘cs-NovΓ‘k; πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 German βš– 181 KB

A mixture of cosolvents is described that significantly improves the solubility of most pharmaceutical compounds. The mixture consists of equal volumes of MeOH, 1,4-dioxane, and MeCN, thereby containing polar and nonpolar solvents, and is referred to as MDM (from MeOH, dioxane, and MeCN). MDM is mix