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A Concise Synthesis of Spirotryprostatin A

โœ Scribed by Miyake, Fumiko Y.; Yakushijin, Kenichi; Horne, David A.


Book ID
120443815
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
53 KB
Volume
6
Category
Article
ISSN
1523-7060

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The Total Synthesis of Spirotryprostatin A. -Key step in the synthesis of the title alkaloid (XI) which is found in the fermentation broth of Aspergillus fumigatus and which manifests cell cycle inhibition at the G2/M phase, is the rearrangement of a bromohydrin prepared in situ from ฮฒ-carboline de