𝔖 Bobbio Scriptorium
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A concise synthesis of either enantiomer of azatyrosine

✍ Scribed by Margaret S. Cooper; Alison W. Seton; Malcolm F.G. Stevens; Andrew D. Westwell


Book ID
103983597
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
221 KB
Volume
6
Category
Article
ISSN
0960-894X

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## Abstract The accumulation of psychosine (galactosyl sphingosine) has been associated with the pathogenesis of Krabbe disease; however, the exact mechanism of its cytotoxicity remains unclear. Herein, we describe the synthesis of the unnatural enantiomer of erythro‐sphingosine, psychosine, and re