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A Concise Stereoselective Synthesis of Orthogonally Protected Lanthionine (VII) and β-Methyllanthionine (IV).

✍ Scribed by Steven L. Cobb; John C. Vederas


Publisher
John Wiley and Sons
Year
2007
Weight
28 KB
Volume
38
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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A Concise and Stereoselective Synthesis
✍ Misiti, Domenico ;Zappia, Giovanni ;Monache, Giuliano Delle 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 469 KB

## Abstract A stereoselective synthesis of __threo__‐γ‐hydroxy‐β‐l‐lysine lactone is reported. The __threo__‐amino alcohol functionality is introduced by iodine‐mediated cyclocarbamation of the electron poor allylamine 6. The D‐phenylalanine was used as starting material as synthetic equivalent to