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A concise route to phytosphingosine from lyxose

โœ Scribed by Chun-Cheng Lin; Gang-Ting Fan; Jim-Min Fang


Book ID
104253936
Publisher
Elsevier Science
Year
2003
Tongue
French
Weight
160 KB
Volume
44
Category
Article
ISSN
0040-4039

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โœฆ Synopsis


Phytosphingosine was synthesized from the commercially available D-2,3-O -isopropylidene-D-lyxofuranose in 28% overall yield by a six-step procedure. This procedure is expedient and flexible for introduction of other lipid moieties on the phytosphingosine structure to make a variety of derivatives that can support the further exploration of their related biological functions.


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