The first total synthesis of (À)-bitungolide E is described. The key steps include a Myers' alkylation, modified Evans' syn aldol-reaction, using Crimmins protocol, Sharpless asymmetric epoxidation and ringclosing metathesis reaction.
✦ LIBER ✦
A concise approach for the synthesis of bitungolides: total syntheses of (−)-bitungolide B & E
✍ Scribed by Reddy, K. Mahender; Shashidhar, J.; Ghosh, Subhash
- Book ID
- 127051127
- Publisher
- Royal Society of Chemistry
- Year
- 2014
- Tongue
- English
- Weight
- 528 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1477-0520
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