A chemoenzymatic and enantioselective to
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Andrew Lin; Anthony C. Willis; Martin G. Banwell
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Article
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2010
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Elsevier Science
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French
β 516 KB
The structure, 5, assigned to the resorcylic acid lactone L-783,290 has been prepared for the first time and in a modular fashion using a Heck reaction to link the readily available fragments 8 and 14. Chemoenzymatic methods were used to prepare the latter fragment, in enantiopure form, from chlorob