Synthesis and regioselective alkylation
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Vincent J Colandrea; Elizabeth M Naylor
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Article
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2000
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Elsevier Science
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French
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A regioselective alkylation of naphthyridines 4a-d, through the action of ethylchloroformate and benzylstannane 5, afforded the benzyl substituted dihydronaphthyridines 3a-d. These key intermediates 3a-d were transformed into the desired targets 2a-d in seven steps.