A very efficient algorithm for determining the geometrically feasible binding modes of a flexible ligand molecule at the receptor site is presented. It is based on distance geometry but maintains the requirements of three dimensions. The distance geometry manipulation can superimpose two bodies with
โฆ LIBER โฆ
A computer simulation of the binding between flexible ligands and their polymeric receptor binding sites
โ Scribed by R.L. Humphries
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- English
- Weight
- 808 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0022-5193
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Geometrically feasible binding modes of
โ
Arup K. Ghose; Gordon M. Crippen
๐
Article
๐
1985
๐
John Wiley and Sons
๐
English
โ 778 KB
Delineation of Receptor-Ligand Interacti
โ
Aldo Jongejan; Rob Leurs
๐
Article
๐
2005
๐
John Wiley and Sons
๐
English
โ 313 KB
๐ 2 views
## Abstract Histamine H~1~ antagonists or โantihistaminesโ are one of the most prescribed drug families in Western countries. They exert their effect by binding to the histamine H~1~ receptor, a receptor belonging to the class of rhodopsinโlike G proteinโcoupled receptors (GPCRs). In this review, t
Exploring subtype selectivity and metabo
โ
Samuel Hintermann; Konstanze Hurth; Joachim Nozulak; Marina Tintelnot-Blomley; R
๐
Article
๐
2011
๐
Elsevier Science
๐
English
โ 493 KB
Interaction between GABA- and Clโ-ionoph
โ
Yu. A. Blednov; M. L. Gordei; S. B. Seredenin
๐
Article
๐
1990
๐
Springer US
๐
English
โ 228 KB
Computer simulations of the kinetics of
โ
Philip W. Kuchel; Keith Dalziel
๐
Article
๐
1980
๐
Elsevier Science
๐
English
โ 468 KB
Synthesis of the Four Stereoisomers of 1
โ
Claus-Jรผrgen Koch; G. Hรถfner; Kurt Polborn; Klausย Theodor Wanner
๐
Article
๐
2003
๐
John Wiley and Sons
๐
English
โ 194 KB
๐ 1 views