A Computational Study on Addition of Grignard Reagents to Carbonyl Compounds
โ Scribed by Yamazaki, Shoko; Yamabe, Shinichi
- Book ID
- 120303030
- Publisher
- American Chemical Society
- Year
- 2002
- Tongue
- English
- Weight
- 292 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0022-3263
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract For Abstract see ChemInform Abstract in Full Text.
A catalytic asymmetric conjugate addition reaction of organocopper reagents, generated from copper salt, a chiral phosphine, and Grignard reagent, with cyclohexenone is highly dependent on the counter anion of copper species, solvents, Grignard reagents, and the structure of the chiral phosphine. Th
The enantioselective copper-catalyzed 1,4-addition of Grignard reagents to a$-unsaturated carbonyl compounds was studied with the following Cu' compounds as catalyst precursor and 1,2 : 5,6-di-0 -isopropylidene-3thio-a -o-glucofuranose (Hsiig) as chiral ligand: CuI, iodo[bis(dibutylsulfide)]copper(I