Numerous lines of evidence have now implicated 7,8-diol-9,10-epoxides as metabolically formed ultimate carcinogens from the environmental contaminant benzo[alpyrene. ly2 In an attempt to generalize the concept of diol epoxides3 as ultimate carcinogens, we have attempted to predict which of the sever
A comprehensive study of isoskeletal analogs of dibenzo[a,c]anthracene
β Scribed by Jerry Ray Dias; Binglan Liu
- Publisher
- Springer Vienna
- Year
- 1990
- Tongue
- English
- Weight
- 922 KB
- Volume
- 121
- Category
- Article
- ISSN
- 0026-9247
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π SIMILAR VOLUMES
An unequivocal synthesis of dihydrodiols of the mutagenic polycyclic aromatic hydrocarbon, dibenz(a,c)anthracene is described An important aspect of polynuclear aromatic hydrocarbon (PAH)-induced carcinogenesis concerns the mechanism by which these relatively inert molecules are metabolically activa
## Dimethylamino infrared at 1674-1682 cm-1 and sulfonate bands at 1360 and 11 50 cm-1. This cyclization corresponds to the formation of cr-pyrones from vinylogous carboxamides and ketene [3].
## Abstract A new convenient method for the synthesis of the title compounds (V) and (IX) and the thiopheneβcontaining picene derivative (XIII) is developed.