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A complete genomic screen for multiple sclerosis underscores a role for the major histocompatability complex

✍ Scribed by Haines, J.L.; Ter-Minassian, M.; Bazyk, A.; Gusella, J.F.; Kim, D.J.; Terwedow, H.; PericakVance, M.A.; Rimmler, J.B.; Haynes, C.S.; Roses, A.D.


Book ID
109916728
Publisher
Nature Publishing Group
Year
1996
Tongue
English
Weight
327 KB
Volume
13
Category
Article
ISSN
1061-4036

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Multiple sclerosis (MS) is a demyelinating disease of the central nervous system with a complex genetic background. In order to identify loci associated with the disease, we had performed a genome screen initially using 6000 microsatellite markers in pooled DNA samples of 198 MS patients and 198 con