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A Novel Role for the Major Histocompatibility Complex Class II Transactivator CIITA in the Repression of IL-4 Production

✍ Scribed by Tania Gourley; Stacey Roys; Nicholas W Lukacs; Steven L Kunkel; Richard A Flavell; Cheong-Hee Chang

Book ID: 117722466
Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 204 KB
Volume: 10
Category: Article
ISSN: 1074-7613
DOI: 10.1016/s1074-7613(00)80037-0

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## Communicated by Henrik Dahl MHC class II deficiency is a severe primary immunodeficiency characterised by the absence of major histocompatibility complex class II (MHC-II) gene expression. It is genetically heterogeneous and can result from defects in at least four different trans-acting regula