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A comparison on effects of normalisations in the detection of differentially expressed genes

โœ Scribed by Monica Chiogna; Maria Sofia Massa; Davide Risso; Chiara Romualdi

Book ID
114998880
Publisher
BioMed Central
Year
2009
Tongue
English
Weight
483 KB
Volume
10
Category
Article
ISSN
1471-2105

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In this study, altered gene expression in five methylnitrosourea (MNU)-induced rat mammary adenocarcinomas was investigated using a newly developed competitive cDNA library screening assay. In order to detect the differentially expressed cDNA transcripts, three cDNA libraries (rat mammary, rat liver